招生资格：硕士生导师

邮箱：zhgyun@tio.org.cn

招生专业：微生物学

研究方向：海洋放线菌资源获取及开发利用

个人简介：

张改云，女，1980年10月出生，博士，副研究员，现任职于自然资源部第三海洋研究所海洋生物遗传资源重点实验室。目前主要从事1，海洋放线菌的多样性研究，包括大洋不同生境放线菌菌株资源获取、分类及其潜力评估；2，基于基因组信息的新颖天然产物的挖掘；3，微生物次级代谢产物关键合成途径的基因功能研究。主持或参与项目包括国家自然科学基金、福建省自然科学基金、厦门海洋研究开发院共建项目、所基本科研业务费、厦门南方海洋研究中心项目、海洋公益性项目及大洋协会项目等。发表学术论文46篇，其中SCI论文32篇；第一作者及通讯作者论文30篇（SCI论文22篇）；申请发明专利6项，授权4项。

发表文章：

1) Wu Q, Deering RW, Zhang G, Wang B, Li X, Sun J, Chen J, Zhang H, Rowley DC, Wang H. 2018. Albisporachelin, a New Hydroxamate Type Siderophore from the Deep Ocean Sediment-Derived Actinomycete WP1. Mar Drugs.16(6)

2) Wu Q, Zhang G, Wang B, Li X, Yue S, Chen J, Zhang H, Wang H. 2018. Production and Identification of Inthomycin B Produced by a Deep-Sea Sediment-Derived Streptomyces sp. YB104 Based on Cultivation-Dependent Approach. Curr Microbiol. 75(7). https://doi.org/10.1007/s00284-018-1469-1.

3) Gaiyun Zhang​, Lina Wang​, Jinglong Li​, Yuan Zhou. 2017. ​Pseudonocardia profundimaris sp. nov., isolated from marine sediment. Int J Syst Evol Microbiol 67: 1693-1697.

4) S Niu, TT Zhou, CL Xie, GY Zhang, XW Yang. 2017. Microindolinone A, a Novel 4,5,6,7-Tetrahydroindole, from the Deep-Sea-Derived Actinomycete Microbacterium sp. MCCC 1A11207. Mar Drugs 15(7).

5) Wang S​, Zhou Y, Zhang G. 2016. Nocardioides flavus sp. nov., isolated from marine sediment. Int J Syst Evol Microbiol. 66: 5275-5280.

6)  CL Xie, SW Niu, TT Zhou, GY Zhang, Q Yang, XW Yang. 2016. Chemical constituents and chemotaxonomic study on the marine actinomycete Williamsia sp. MCCC 1A11233. Biochemical Systematics and Ecology. 67:129-133.

7) Zhang G, Yang Y, Wang L. 2016. Altererythrobacter aurantiacus sp. nov., isolated from deep-sea sediment. Antonie Van Leeuwenhoek. 109(9):1245-1251.

8) Zhang G, Wang L, Li J, Zhou Y. 2016. Amycolatopsis albispora sp. nov., isolated from deep-sea sediment. Int J Syst Evol Microbiol. 66: 3860-3864.

9) Wang L, Li J, Zhang G. 2016. Nocardioides rotundus sp. nov., isolated from deep seawater. Int J Syst Evol Microbiol. 66(5):1932-1936.

10) Zhang G​, Wang S​, Wang L.​ 2016. Sediminivirga luteola gen. nov., sp. nov., a member of the family Brevibacteriaceae, isolated from marine sediment. Int J Syst Evol Microbiol. 66: 1494-1498.

11) Wang S, Xu X, Wang L, Jiao K, Zhang G. 2015. Georgenia subflava sp. nov., isolated from a deep-sea sediment. Int J Syst Evol Microbiol. 65:4146-4150.

12) Zhang G, Yang Y, Wang S, Sun Z, Jiao K. 2015. Alkalimicrobium pacificum gen. nov., sp. nov., a marine bacterium in the family Rhodobacteraceae. Int J Syst Evol Microbiol. 65: 2453-2458

13) Zhang G, Zhang Y, Yin X, Wang S. 2015. Nesterenkonia alkaliphila sp. nov., a novel alkaliphilic, halotolerant actinobacteria isolated from the western Pacific Ocean. Int J Syst Evol Microbiol. 65( 2): 516-521.

14)  Yin X, Yang Y, Wang S, Zhang G. 2015. Virgibacillus oceani sp. nov. isolated from ocean sediment. Int J Syst Evol Microbiol. 65:159–164.

15)  XW Yang, Z Miao, XN Ma, GY Zhang, A Steinmetz. B Yang, JF Wang, J Liu, YH Liu, N Wang. 2015. Asterolloside, a novel enolic saccharide from the sea star Asterias rollestoni Bell. Tetrahedron Letters. 56:6174–6176.

16) Zhang G, Yang Y, Yin X, Wang S. 2014. Paracoccus pacificus sp. nov., isolated from the Western Pacific Ocean. Antonie Van Leeuwenhoek. 106(4):725-731.

17) Yang Y, Zhang G, Sun Z, Cheung MK, Huang C. 2014. Altererythrobacter oceanensis sp. nov., isolated from the Western Pacific. Antonie Van Leeuwenhoek. 106(6):1191-1198.

18) Zhang Y, Ren H, Zhang G. 2014. Microbacterium hydrothermale sp. nov., an actinobacterium isolated from the Indian Ocean. Int J Syst Evol Microbiol. 64(Pt10): 3508-3512.

19) Zhang G, Ren H, Wang S, Chen X, Yang Y, Zhang Y, Jiang Y. 2014. Janibacter indicus sp. nov., isolated from hydrothermal sediment of the Indian Ocean. Int J Syst Evol Microbiol. 64(Pt 7):2353-2357.

20) Zhang G, Ren H, Chen X, Zhang Y, Yang Y, Wang S, Jiang Y. 2014. Sporosarcina siberiensis sp. nov., isolated from the East Siberian Sea. Antonie Van Leeuwenhoek. 106(3):489-495.

21) Zhang G, Cao T, Ying J, Yang Y, Ma L. 2014. Diversity and novelty of actinobacteria in Arctic marine sediments. Antonie Van Leeuwenhoek. 105( 4): 743-754.

22) Yang XW, Peng K, Liu Z , Zhang GY, Li J, Wang N, Steinmetz A, and Liu YH. 2013. Strepsesquitriol, a Rearranged Zizaane-Type Sesquiterpenoid from the Deep-Sea-Derived Actinomycete Streptomyces sp. SCSIO 10355. J. Nat. Prod. 76 (12), pp 2360–2363

23) Zhang G，Ren H，Zhang Y, Ma L, Yang Y, Wang S. 2013. Chemical constituents of the starfish Asterias rollestoni Bell. Biochemical Systematics and Ecology. 51：203-206.

24) Chen R, Zhang H, Zhang G, Li S, Zhang G, Zhu Y, Liu J, Zhang C. 2013.Characterizing Amosamine Biosynthesis in Amicetin Reveals AmiG as a Reversible Retaining Glycosyltransferase. JACS. 135 (33):12152–12155 (IF=10.677)

25) Zhang G, Zhang H, Li S, Xiao J, Zhang G, Zhu Y, Niu S, Ju J, Zhang C. 2012. Characterization of the Amicetin Biosynthesis Gene Cluster from Streptomyces vinaceusdrappus NRRL 2363 Implicates Two Alternative Strategies for Amide Bond Formation. Applied and Environmental Microbiology. 78(7):2393-2401.

26) Yang XW, Zhang GY, Ying JX, Yang B, Zhou XF, Steinmetz A, Liu YH, Wang N. 2013. Isolation, Characterization, and Bioactivity Evaluation of 3-((6-Methylpyrazin-2-yl) methyl)-1H-indole, a New Alkaloid from a Deep-Sea-Derived Actinomycete Serinicoccus profundi sp. nov. Mar Drugs. 11(1):33-39.

27) Zhang W, Liu Z, Li S, Lu Y, Chen Y, Zhang H, Zhang G, Zhu Y, Zhang G, Zhang W, Liu J, Zhang C. 2012. Fluostatins I-K from the South China Sea-Derived Micromonospora rosaria SCSIO N160. J Nat Prod. 75 (11):1937–1943.

28) Xiao Y, Li S, Niu S, Ma L, Zhang G, Zhang H, Zhang G, Ju J, Zhang C. 2011. Characterization of Tiacumicin B Biosynthetic Gene Cluster Affording Diversified Tiacumicin Analogs and Revealing a Tailoring Di-halogenase. J. Am. Chem. Soc. 133 (4):1092–1105. 

29) Zhang G, Chen M, Chen X, Xu Z, Li L, Guo J, Ma Y. 2010. Isolation and characterization of a novel EAR-motif-containing gene GmERF4 from soybean (Glycine max L.). Mol Biol Rep. 37:809–818.

30) Zhang G, Chen M, Li L, Xu Z, Chen X, Guo J, Ma Y. 2009. Overexpression of the soybean GmERF3 gene, an AP2/ERF type transcription factor for increased tolerances to salt, drought, and diseases in transgenic tobacco. J Exp Bot. 60:3781-3796.

31) Zhang G, Chen M, Guo J, Xu T, Li L, Xu Z, Ma Y, Chen XP. 2009. Isolation and Characteristics of the CN Gene, a Tobacco Mosaic Virus Resistance N Gene Homolog, from Tobacco. Biochem Genet. 47(3-4):301-314. 

32)  Zhang G, Chen M, Chen X, Xu Z, Guan S, Li LC, Li A, Guo J, Mao L, Ma Y. 2008. Phylogeny, gene structures, and expression patterns of the ERF gene family in soybean (Glycine max L.). J. Exp. Bot. 59: 4095 - 4107.